Enucleation for ameloblastoma lesions frequently produce a recurrence. Radical resection, therefore, has become the most widely used from of therapy. Even after radical resection, however, the recurrence may be produced. This case is reported because the tumor recurred rarely at two sites after hemimandibulectomy; A-31-year old woman received hemimandibulectomy and immediate reconstruction of mandible with iliac bone in 1964. In 1980 and 1985, tumor recurrences were found at the molar region contacted with iliac bone with the size of tip of an index and temporal region with the size of 7×7×4cm, respectively. Both tumors were removed and at present the patient is tumor-free without complications.