1987 Volume 33 Issue 11 Pages 2271-2277
Clinical study of 6315-S (FMOX, Flomoxef) in various infections in the field of oral surgery were carried out. 6315-S was administered by intravenous injection at a daily dose of 2 g (1 g×2 times) to 25 patients with various infections.
Cases consisted of 16 with maxillary ostisis, 4 phlegmon of the floor of the mouth, 2 peritonsillar abscess, 1 pericoronitis, 1 palatal abscess and 1 sialoadenitis submandibularis.
The following results were obtained. The clinical effects obtained in subjective judgement were excellent in 5 cases, good in 15 cases, fair in 4 and poor in 1. The clinical effects obtained in judgement by point were classified as excellent in 5 cases, good in 19 and poor in 1. Effective rate in subjective was 80.0%. Effective rate in judgement by point was 96.0%.
The only side effect was diarrhea in one case.
In the laboratory examinations, elevations of s-GOT and s-GPT in one case were observed.
The results indicated the usefulness of 6315-S in the treatment of various infections in the field of oral surgery.