We have reported a case of 65 year-old woman in which a large neurilemmoma occurred in the infratemporal fossa and presented clinically as a swelling in the cheek. It contained a cystic degeneration cavity and inner fluid.
The tumor was removed en block by intraoral surgical approach. Histopathological findings were neurilemmoma (Antoni A and B type). Biochemical analysis of the inner fluid revealed declination of protein involvement compared to serum.