口腔領域における重複癌の自験12症例

抄録

Multiple primary cancer was first recorded by Billroth in 1889, since then the number of cases reported has increased every year. Opportunities for the discovery of synchrous or metachronous multiple primary cancer have accompanied the development of therapy and diagnosis techniques for malignant tumors.
In the 9 years from 1976 to 1985, our oral surgery division detected 12 cases of multiple primary cancer out of the 128 cases of oral cancer treated. We analyzed the occurrence and the different combination of organs in which multiple primary cancer occurs.5 of the 12 cases located within the same oral region were found to be multiple primary cancer (41.7%). There were 2 cases where the occurrence of epidermoid carcinoma was detected in the previously affected area, occurring long after the radiation therapy treatment of tongue cancer ended. In regard to the periodic examinations which follow oral cancer treatment, special consideration should be given to the detection of multiple primary cancer, as well as the regeneration and spread of primary cancer. Periodic examinations are an important part of the follow-up process, and continue to play an important role long after radiotherapy treatment has ended.