Clinical study on maxillo-oral malignant tumor 2. Chemotherapy with peplomycin on oral cancer (squamous cell carcinoma)

Shigeru OHYAMA; Wataru SOEJIMA; Kouji FUJIWARA; Hisato KAMURA; Toshihiko NARUSE; Masaaki KOGA; Masaaki GOTO; Takeshi KATSUKI

doi:10.5794/jjoms.33.753

Clinical study on maxillo-oral malignant tumor

2. Chemotherapy with peplomycin on oral cancer (squamous cell carcinoma)

Shigeru OHYAMA, Wataru SOEJIMA, Kouji FUJIWARA, Hisato KAMURA, Toshihiko NARUSE, Masaaki KOGA, Masaaki GOTO, Takeshi KATSUKI

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Keywords: Intra-arterial infusion, Peplomycin, Radiation Therapy

JOURNAL FREE ACCESS

1987 Volume 33 Issue 4 Pages 753-759

DOI https://doi.org/10.5794/jjoms.33.753

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Abstract

The primary sites of cancer cases were: 5 tongue, 6 oral floor, 5 gingiva, 3 hard palate and 1 cheek.
The clinical stages were: stage I 2 cases, stage II 10 cases, stage III 5 cases and stage IV 3 cases.
The clinical results obtained were recorded as excellent (complete response) in 11 cases (55%), effective in 7 cases (35%) and moderate in 2 cases (10%).
9 of 11 cases observed complete response were treated with Peplomycin (intra-arterial infusion) combined with radiation therapy.
We present the results and complications of 20 cases.

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