Effect of afloqualone (Arofuto) on tonic vibration reflex of the masticatory muscle
1987 Volume 33 Issue 5 Pages 1034-1038
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1987 Volume 33 Issue 5 Pages 1034-1038
The authors examined the efficacy of afloqualone (Arofuto®) a centrally acting muscle reluctant, on the neuromuscular system of mastication, by monitoring the magnitude of biting force exerted from a tonic vibration reflex of the masticatory muscles, particularly the masseter. The reflex was evoked by a mechanical vibration given to the muscle. Afloqualone (40mg) was orally administered to 10 healthy adult volunteers for this examination.
The mean magnitude of the biting force was significantly reduced from 7.2kg before administration, to 5.0, 3.5 and 5.4kg at 30, 60 and 120 minutes, respectively, after the administration (P<0.01). This result seems to indicate that the use of afloqualone may be of value to patients in acute myofascial pain dysfunction syndrome.
