Oral candidiasis has greatly increased in compromised hosts for an opportunistic fungus infection. Chronic mucocutaneous candidiasis (CMCC) is a chronic and persistent infection of the skin, the nails and mucous membranes associated with a selective defect in cell-mediated immunity.
The case of a 60-year-old man with concurrent late-onset CMCC, myasthenia gravis and thymoma was reported. This late-onset CMCC is unique in that the infection begin after the third decade and almost each patient has thymoma. To the best of our knowledge, about 30 patients with CMCC and tymoma have reviewed. However some evidence of impaired cell-immunity were found in these patients, in the case reported here, no immunological defects were demonstrated except neutrophil dysfunction.