1988 Volume 34 Issue 10 Pages 2246-2251
Mucous membrane pemphigoid is a vesiculobullous disease of unknown etiology which is relatively uncommon.
This disease is diagnosed on the basis of histopathologic and immunofluorescence studies in biopsy of the oral mucosa.
A 62-year-old woman with erosion on the gingiva visited our clinic.
Oral examination revealed erosion on the gingiva. Histopathological features showed a definite subepithelial vesicle formation and t nonspecific chronic inflammatory infiltrate in the connective tissue. The entire epithelium was intact and no evidence of acantholysis was found.
The results of direct immunofluorescent staining demonstrated a linear basement membrane zone pattern with IgG and C3.
The diagnosis of mucous membrane pemphigoid was established.
Although the oral lesion has not healed completely after 2 years of observation, the patient's symptoms were alleviated by topical steroid therapy and by brushing after scaling. The clinical and histopathological characteristics of mucosal pemphigoid were discussed.
