Clinicopathological study of the squamous cell carcinoma of the lower gum

Abstract

A histological classification and grading of malignancy was evaluated on the initial biopsy specimens from 38 patients with squamous cell carcinoma of the lower gum in the Department of Oral and Maxillofacial Surgery at Kyoto University Hospital during the past 20 years.
Malignancy points were investigated by means of Willén's method and the materials were classified into three groups; low malignant group (<14), moderate malignant group (14≤, ≤16) and high malignant group (16<).
The low malignant group patients showed a cumulative five years survival rate of 41.3%, on the other hand, lower survival rate was found in the high malignant group, with a cumulative five years survival rate of 22.2%.
This study suggested the positive relationship between a histological grading of malignancy and the clinical course in gingival cancer patient.