Japanese Journal of Oral and Maxillofacial Surgery
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Experimental study on the cleft lip and palate
lnduction of cleft plate in wistar imamichi rats by suspension of dexamethasone
Shoji INAGAKINagato NATSUMEShigeki MIURAHiroshi FUJIWARAShuichi SUGIMOTOTsuyoshi KAWAI
Author information
JOURNALS FREE ACCESS

1989 Volume 35 Issue 1 Pages 80-85

Details
Abstract

Wistar Imamichi rats were given a single subcutaneous injection of suspension of dexamethasone from the 9 th day to the 12 th day of gestation. Cleft palates in the fetuses were observed after rats were sacrificed with ether inhalation followed by cervical dislocation at the 20 th day of gestation.
In the group administered 1. 6 mg of dexamethasone, the incidence of cleft palate was 64. 6% at the 10 th day of gestation. In the group administered 3. 2 mg of dexamethasone, the incidence of cleft palate was 78. 7% at the 11 th day of gestation. They both showed high rates.
We thought that this method

Information related to the author
© Japanese Society of Oral and Maxillofacial Surgeons
Previous article Next article
feedback
Top