日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
OK432の局所投与が反対側頸部転移病巣の著明な腫瘍縮小効果を示した上顎歯肉癌症例
大倉 正也白砂 兼光吉岡 秀郎松矢 篤三
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1990 年 36 巻 3 号 p. 580-583

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A metastasis was recognized in the contralateral lymph node after radiation therapy and surgical operation including ipsilateral radical neck disection and primary tumor excision for gingival squamous cell carcinoma (T3N2bM0). Intramuscular injection of pepleomycin was initially carried out with no tumor regression. In addition to the above chemotherapy, therefore, we treated this patient with intratumoral injection of OK-432, resulting in marked reduction in size of the metastatic lesion. It is thus suggested that intratumoral administration of OK-432 with or without chemotherapy maybe effective for such a recurrent case of oral cancer.

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