We have recently experiencd a case of large ameloblastoma with severe hypoproteinemia. The patient was a 34-year-old man, who was pointed out the existence of ameloblastoma in the left molar region of the mandible 13 years ago in our hospital, but refused to receive a therapy for ameloblastoma. After 13 years, he came to our hospital with a complaint of airway obstruction. He had a difficulty in eating, so his general condition was very bad. Especially, he had severe hypoproteinemia as total protein in his blood was 3.0g/dl. We tried to recover his general condition but failed to normalize his hypoproteinemia because of a leak of serum through a fistula opening in the oral cavity. Before the treatment for restoration sudden bleeding from the tumor compelled us to perform an operation, but we could not resect all of the tumor because of massive bleeding. After that, we used a sclerosing agent. Though it was locally effective, his general condition became worsened and he ultimately died of lung edema.
We report a case of advanced ameloblastoma with severe hypoproteinemia.
