1991 Volume 37 Issue 2 Pages 380-386
A case of Apert syndrome with cleft palate is presented. The fetures of the case were characterized by acrocephaly syndactly of hands and feet, facial abnormality, maxillary hypoplasia and cleft palate.
Craniofacial pattern analyses were carried out by lateral roentogenographic cephalogram. The results slowed maxillary hypoplasia. Furthermore, the rate of area between cranial and facial space was measured with CARDIAS GP 2, 000 (Nac CO. JAPAN), ard it was showed that the cranial space of this case was smaller than the average values of normal children.
With regard to the clinical findings and the craniofacial pattern, his mother showed a strong similarity. Moreover, she was given many drugs, including som, antibiotics, for hepatitis therapy early in her pregnancy. As stated above, it is assumed that hereditary and/or environmental factors were the cause or causes of the abnormalities.