We presented two cases of calcifying epithelioma in the parotid-masseteric region. One was a 59-year-old woman, and the other was a 38-year-old man. Both cases had been aware of persistent subcutaneous nodules in the region for about thirty years. The nodules were painless, well-defined, movable and firm.
A clinical diagnosis of calcifying epithelioma was made and the tumors were enucleated. There was minimal adherence between the tumors and the surrounding tissues. The enucleated tumors measured 28 × 17 × 7 mm and 20 × 13 × 7 mm, respectively.
Histopathologically, they were composed of distinctly bordered nests or masses of shadow cells which possessed a central unstained area due to nuclear loss. Few basophilic cells and large areas of calcification were observed. In part of the tumors, a little bone formation was also observed.
The postoperative progress of the two patients is satisfactory without recurrence.
