Angiofibroma is a rare type of benign tumor. It mostly occurs in the nasopharyngeal area of juvenile males. A huge angiofibroma in the right cheek of a 76-year-old female is described. The tumor was removed under local anesthesia with an intraoral approach. It measured 70×85 mm and weighed 150 g. The histopathological diagnosis was angiofibroma. Her progress has been favorable 23 months after the operation.