41 巻 (1995) 10 号 p. 893-895
This report describes the hemostatic management of a 7-year-old boy with conge-nial hypoprothrombinemia who underwent intraoral surgery. One hour before operation, the serum prothrombin level was increased from 1.7% to 130% by infusion of prothrombin com-plex concentrate (PCC; prothrombin dose: 60 units/kg). The patient underwent extractionof E and B, and marsupialization of a 7 dentigerous cyst, and prompt hemostasiswas obtained by a combination of gauze-tamponade and hemostatic splinting.
Serum prothrombin was maintained at a level of more than 40% for one week by infusionof PCC (prothrombin dose: 30 units/kg) on the 2nd, 4 th and 7 th postoperative days. Postoperative bleeding did not occur at the surgical field. We conclude that adequatehemostasis can be obtained by PCC (prothrombin dose: 60 units/kg) infusion and properlocal hemostatic management, in patients with congenital hypoprothrombinemia who un-dergo intraoral surgery.