日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
口腔内止血管理を行った先天性低プロトロンビン血症患児の1例
森本 佳成湯村 典子河野 孝行杉村 正仁中島 充吉岡 章
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41 巻 (1995) 10 号 p. 893-895

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This report describes the hemostatic management of a 7-year-old boy with conge-nial hypoprothrombinemia who underwent intraoral surgery. One hour before operation, the serum prothrombin level was increased from 1.7% to 130% by infusion of prothrombin com-plex concentrate (PCC; prothrombin dose: 60 units/kg). The patient underwent extractionof E and B, and marsupialization of a 7 dentigerous cyst, and prompt hemostasiswas obtained by a combination of gauze-tamponade and hemostatic splinting.
Serum prothrombin was maintained at a level of more than 40% for one week by infusionof PCC (prothrombin dose: 30 units/kg) on the 2nd, 4 th and 7 th postoperative days. Postoperative bleeding did not occur at the surgical field. We conclude that adequatehemostasis can be obtained by PCC (prothrombin dose: 60 units/kg) infusion and properlocal hemostatic management, in patients with congenital hypoprothrombinemia who un-dergo intraoral surgery.

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