Abstract
Head and neck cancers are frequently combined with other primary lesions in the head and neck area or in the digestive tract, especially the esophagus and stomach. Therefore, most multiple primary cancers are pathologically squamous cell carcinoma and adenocarcinoma.
We report a case of carcinoma of the oral floor in a 69-year-old man with malignant reticulosis, which is one of the rare mesenchymal tumors. The primary carcinoma of oral floor was completely eradicated by chemotherapy and radiotherapy; however, the patient died from pancytopenia of unknown cause and multiple organ failure. Pathological examination at autopsy revealed squamous cell carcinoma of oral floor with malignant reticulosis involving the spleen, liver, bone mallow, lung and lymph nodes.