The hemolytic uremic syndrome (HUS) is a heterogeneous disorder characterized by hemolytic anemia, thrombocytopenia, and renal failure, occurring predominantly in infants and young children. Recently HUS in adults has been described as a complication of anti cancer chemotherapeutic agents.
A 53-year-old man who was being treated for squamous cell carcinoma of the tongue developed chemotherapy-induced HUS during operation after receiving neo-adjuvant chemotherapy. Plasma exchange was carried out four times besides blood transfusion and hemodialysis therapy. His renal function was gradually improved, and he also recovered from anemia and thrombocytopenia.