A case of leiomyosarcoma of the palate in a 41-year-old man is reported. A thumbsized tumor was found on the palate, behind the right upper incisor and first premolar. Leiomyosarcoma was diagnosed on histopathological examination of a biopsy specimen, and a partial maxillectomy was performed. The tumor underwent immunohistochemical and electron microscopic studies to confirm the diagnosis of leiomyosarcoma.
