We studied 13 male cases of Sjögren's syndrome (SS). The incidence of periductal lymphocytic infiltration of the labial glands, parotid glands, or both in the male cases was 18%(2/11), which was significantly (P<0.01) lower than that in female cases (133/195: 68%). The rate of patients with keratoconjunctivitis sicca (KCS) was higher in males than in females, although the difference was not statistically significant. There were no marked differences in the incidence of SS-related sialographic findings or the rate of patients with any other autoimmune diseases between the male and female patients.
