1997 Volume 43 Issue 6 Pages 496-498
Leiomyosarcoma, a malignant lesion of smooth muscle origin, is rare in the oral region.
A case of leiomyosarcoma of the mandible is reported. A 86-year-old woman was referred to our hospital because of a mass in the mandibular incisor region. A hens' egg-sized, elastic hard tumor was found in the mandibular incisor region. Leiomyosarcoma was diagnosed on histopathological examination of a incisional biopsy specimen. Surgical resection was not performed because the tumor showed evidence of extensive invasion and the patient refused surgery. Radiation therapy (40 Gy) and chemotherapy with cisplatin and caffeine were administered. The growth of the tumor was apparently suppressed. However, the patient died 34 months after presentation.