We histomorphologically analyzed the interface between grafted bone and titanium implants in retrieved en-bloc material. The patient had squamous cell carcinoma of the maxilla at the left molar region. Maxillary sinus augmentation of the right side was carried out with an autogenous iliac bone graft at the time of partial maxillectomy. Implants were placed secondarily. Clinically, however, osseointegration was not completed. Histologically, the grafted bone was not in contact with the implant, and fibrous connective tissues were observed at the bone-implant interface. Irradiation and chemotherapy before surgery may have prevented remodeling of the grafted bone and osseointegration.
