日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
HIV感染者に生じた口腔病変の検討
CD4陽性リンパ球数に基づいた臨床ステージと口腔病変との関連
上海道 範昭森本 佳成山本 一彦杉浦 勉遠藤 武弘杉村 正仁
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1998 年 44 巻 7 号 p. 640-642

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Oral manifestations associated with HIV infection are highly predictive markers of severe immunosupressive status and disease progression. In this report, the oral manifestations of 21 HIV-infected individuals, including 15 AIDS patients are described. Most of the patients (95.2%) had hemophilia. Only one (4.8%) was infected by heterosexual contact. The oral lesions were oral candidiasi (66.7%), herpes simplex virus lesions (28.6%), hairy leukoplakia (19.1%), and HIV-related periodontal disease (4.8%). The oral lesions were clinically similar to those reported in HIV infection in other countries. This study showed that all oral lesions associated with HIV infection increased in frequency when the CD 4+ lymphocyte count fell below 500 cells/mm3.

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