放射線療法が効を奏した頬粘膜部に発生したoral florid papillomatosisの1例

抄録

Oral florid papillomatosis (OFP) is usually associated with progression and recurrence. Radical treatment of OFP is very difficult, although various therapeutic modalities have been proposed, including chemotherapy with anticancer drugs, surgery and radiotherapy.
We report a case of OFP located in the right buccal mucosa in an 80-year-old woman. Clinically, a malignant tumor was suspected, although histological examination showed only hyperplasia with parakeratosis and acanthosis, and there was no evidence of malignant tumor in the specimens. The lesion repeatedly recurred after treatment with CO₂ laser and retinoid (etretinate). Radiotherapy (X-ray) was finally effective.