日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
マウス顎関節滑膜におけるヒアルロン酸結合蛋白 (HABP) およびCD44の発現
山田 耕治覚道 健治酒匂 潤佐々木 昇井関 富雄白数 力也
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ジャーナル フリー

2002 年 48 巻 7 号 p. 349-354

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To examine the distribution of hyaluronic acid (HA) in murine temporomandibular jointsynovium, histochemical and immunohistochemical techniques were employed to study the synovial membrane, using hyaluronic acid binding protein (HABP), which specifically binds to HA, and antibodiesagainst CD44, serving as hyaluronan receptor.
HABP reactivity was detected in synovial lining cells, collagen fibers, and capillaries. CD44 reactivitywas detected on the cell surface of all synovial lining cells. These results suggest that HA is distributed intemporomandibular synovial tissue and that CD44 expressed as hyaluronan receptor is involved in theregulation of HA.

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