Glandular odontogenic cyst (GOC) is a rare jawbone cyst of odontogenic origin, first described by Gardner et al. in 1988. GOC is characterized by typical histopathological features, a gradual increase in size, and a high rate of local recurrence if not adequately treated. We report a case of GOC occurring in the anterior region of the mandible. The patient was a 62-year-old woman who presented with swelling of the anterior region of the mandible. Panoramic radiography indicated a multilocular radiolucent lesion in the anterior region of the mandible. Enucleation of the cyst was performed. Postoperative healing was satisfactory, and no recurrence has been noted on long-term observation. We reviewed 41 cases of GOC that had beenreported previously. Among these cases, 35 were located in the mandible and only 6 in the maxilla. The male: female ratio was 1.28 (23: 18), and the mean age was 47.8 years. Radiographically, among a total of 37 cases, 18 were unilocular and 19 were multilocular. The overall recurrence rate was 19.5%.