A case of adenomatoid odontogenic tumor with calcifying epithelial odontogenic tumor-like areas (so-called combined epithelial odontogenic tumor) occurring in the anterior region of the mandible

Abstract

Combined epithelial odontogenic tumor was first described by Damm in 1982 as a rare tumor characterized by the presence of calcifying epithelial odontogenic tumor (CEOT) areas in adenomatoid odontogenic tumor (AOT). Histologically, the tumor shows relatively small epithelial nests forming duct-like structures and markedly hyalinized fibrous tissue stroma containing amorphous and irregularly shaped calcified tissue and amyloid-like materials. There are several round-shaped masses that show Liesegang rings. This article describes a case of adenomatoid odontogenic tumor with calcifying epithelial odontogenic tumor-like areas, so-called combined epithelial odontogenic tumor, between the right lateral incisor and the left canine region in the mandible.
A 27-year-old woman was referred to our clinic for evaluation of a mixed radiolucent-radiopaque lesion with a well-defined border in the mandible. A computed tomographic scan demonstrated a well-defined large lesion that extended widely, with thinning of the cortical bone of the mandible. The lesion was associated with an impacted canine in the mandible.
Surgery was performed with the patient under general anesthesia.The tumor was enucleated completely via an intraoral approach. Wound healing is currently good, 9 months after surgery.