Abstract
We reported a 13-year-old boy with acute myeloblastic leukemia (AML) having specific chromosomal translocation t (6 ; 9) (p23 ; q34) and marked hypophosphatemia in the terminal stage. He was admitted for fever and hip joint pain. His white blood cell showed to be 35, 300/μl with 92.5 % blasts. His bone marrow showed to be 46, 300/μl with 36.5% blasts which were classifiable as M1 according to the French-American-British (FAB) classification. A chromosomal analysis of bone marrow leukemic cell revealed t (6;9) (p23 ; q34). In spite of various intensive chemotherapy, he did not attain complete remission, and he died after the 5 months since the initiation of induction therapy. Peripheral basophilia appeared during the course of this first treatment, and a marked decrease in serum and urinary phosphates occurred in the terminal stage. We discussed the clinical features of this translocation and hypophosphatemia observed during the course of this patient.
