医療薬学
Online ISSN : 1882-1499
Print ISSN : 1346-342X
ISSN-L : 1346-342X
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多発性硬化症におけるインターフェロン自己注射導入時の薬剤師の介入と役割
藤井 淳子平野 照之前田 寧平原 智雄山下 賢本田 省二内野 誠齋藤 秀之
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2010 年 36 巻 12 号 p. 868-873

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We investigated the role of pharmacists in the treatment of multiple sclerosis (MS) patients (37 cases) based on data obtained during pharmaceutical care services provided to patients regarding self-injection of interferon -β (IFNβ) at the beginning of such treatment,when we provided continuous training in the injection of IFNβ until all patients could inject themselves.We also explained the adverse reactions,and provided further support after they had left hospital.However,at the beginning,all patients had difficulty in mastering the injection technique and were anxious about adverse effects.These problems hindered self-injection.As adverse effects,fever,lassitude and skin lesions developed.The skin lesions tended to become worse with long-term outpatient treatment and this was thought to be due to non-compliance in IFNβ treatment.
Continuous treatment with IFNβ is indispensable in preventing recurrence of MS and maintaining good ADL for patients and we feel that appropriate supportive care provided by pharmacists at the start of IFNβ treatment is effective in ensuring that it is continued.Thus the positive involvement of pharmacists in MS treatment is thought to be necessary and we hope that our efforts will lead to the establishment of standardized pharmaceutical care services for such intractable diseases with relatively few cases.

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© 2010 日本医療薬学会
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