2022 年 48 巻 5 号 p. 194-202
PreAVOID, which refers to cases in which pharmacists avoid or reduce undesirable drug-related issues (eg, adverse drug reactions [ADRs], drug-drug interactions, and insufficient therapeutic effects) by pharmaceutical interventions, have been used as one of the indicators of pharmacists’ professional performance. In recent years, despite the efforts undertaken by community pharmacists to promote PreAVOID, PreAVOID reports by community pharmacists have not been adequately examined. In this study, we analyzed PreAVOID reports by community pharmacists to understand the characteristics of drug-related problems (DRPs) that required pharmaceutical interventions in outpatients and the profession of community pharmacists. We classified DRPs into eight categories and 33 subcategories and analyzed community pharmacists’ pharmaceutical interventions for various DRPs (eg, overdosage, duplication of drugs with similar effects, and history of ADRs). Of note, 70.9％ of the PreAVOID by community pharmacists led to the avoidance of ADRs, and it was estimated that interventions for the avoidance of ADRs in the reported cases alone potentially reduced medical costs by approximately JPY 83 million. These results indicate that community pharmacists contribute to the avoidance of undesirable pharmaceutical issues in patients, mainly by performing interventions that help prevent ADRs. The classification used for DRPs in daily medical practice in this study could help identify DRPs that could be resolved by community pharmacists.
