病院薬学
Online ISSN : 2185-9477
Print ISSN : 0389-9098
血液中の抗てんかん薬の定量
井上 良則本家 忠治
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ジャーナル フリー

5 巻 (1979-1980) 3 号 p. 134-140

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The serum level of antiepileptic drugs (diphenylhydantoin, phenobarbital, carbamazepine and primidone) was determined by modified Kupferberg's gas-liquid chromatography. Since the serum level of these drugs were found to be determined when they are within a therapeutic level, the test was made in children at the age of 3 to 17 years. The range of effective serum level of diphenylhydantoin was estimated at 5 to 10 μg/ml.

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