病院薬学
Online ISSN : 2185-9477
Print ISSN : 0389-9098
注射用アンピシリンナトリウムの他剤混合時における力価の変化
古市 勝久松嶋 幹夫門田 和代安達 美奈子住田 克己
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5 巻 (1979-1980) 4 号 p. 234-240

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The potency of ampicillin is known to be reduced when mixed with glutathione. Halogen or sulfonic acid group is related to the detoxication mechanism of Tathion. In this study, mixtures were prepared first by dissolving Tathion in halogen -or sulfonic acid groupcontaining injections such as Allergin, Metilon and Adona.Then the effect of Viccillin for injection, an ampicillin preparation, added to the mixtures, was examined by bioassay and colorimetry. It was found that the potency of Viccillin is well preserved by adding Allergin, Metilon or Adona mixed with Tathion.

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