緑膿菌, 大腸菌, ブドウ球菌に対するハイアミンTとヒビテン混合消毒液の相乗効果

抄録

Bactericidal effect of mixed disinfectants (10% benzethonium chloride solution: Hyamine-T Solution; 5% chlorhexidine gluconate: Hibitane) was studied. Several strains of Pseudomonas aeruginosa, P. maltophilia, P. cepacia, Escherichia coli and Staphylococcus aureus were used. Minimum inhibitory concentration (MIC) was compared among the two agents and their mixture by the method of Anjo et al. It was found that the mixture showed higher MIC than two other single-entity products, indicating the synergistic effect of the ingredients. The bactericidal effect reached maximum when 10% benzethonium chloride solution and 5% chiorhexidine gluconate were compounded at the ratio of 7: 3.