The Japanese Journal of Physiology
Print ISSN : 0021-521X
COMPARATIVE ACTIVITIES OF NORADRENALINE AND ADRENALINE IN SOME BIOLOGICAL TESTS
THE RABBIT INTESTINE SEGMENT METHOD, THE CAT PARADOXICAL PUPIL REACTION AND THE DOG BLOOD PRESSURE
鈴木 達二中村 照夫蜷川 親正
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ジャーナル フリー

1952 年 3 巻 p. 170-175

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The effects of L-noradrenaline and L-adrenaline on the denervated iris of cats, blood pressure of dogs and intestinal segments of rabbits were compared.
In the cat paradoxical pupil reaction, noradrenaline was equally effective or less effective in comparison with adrenaline. The activity ratio of noradrenaline to adrenaline varied from 0.45: 1 to 1.0: 1, with a mean value of 0.73: L Noradrenaline was more effective on dog blood pressure than adrenaline, and the ratio of activity of noradrenaline to that of adrenaline varied between 1.6: 1 and 2.8: 1, with a mean value of 2.1: 1.
Noradrenaline was found to be more effective than adrenaline on rabbit intestinal segments. The activity ratio was 2.0: 1-3.5: 1, with a mean value of 2.8: 1.
The discrepancy of adrenaline estimates of adrenal extract yielded by various biological methods was discussed.

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