Involvement of Ventromedial Hypothalamus in Brown Adipose Tissue Thermogenesis Induced by Preoptic Cooling in Rats

Abstract

In unanesthetized rats, preoptic (PO) cooling increased brown adipose tissue (BAT) temperature (T_bat). T_bat was kept at a higher level by PO cooling, but lidocaine injected into the ventromedial hypothalamus (VMH) decreased T_bat and saline had no effect. These results indicate VMH is involved in BAT thermogenesis induced by PO cooling.