Low reactive level laser therapy (LLLT) has been applied to a variety of oral disorders, and efforts to prove its effectiveness have been conducted in various basic and clinical studies. Thus, clinical efficacy of LLLT in pain attenuation, wound healing, bone remodeling and neural regeneration, together with clinical safety, has been being recognized. Although no consensus still exists in the literature regarding the parameter and clinical protocol to use in LLLT, higher quality clinical studies, such as randomized clinical trials with placebo controls and systematic reviews with a meta-analysis, have been reported. The aim of this article is to review current evidence on the clinical efficacy of LLLT to various oral disorders, based on the results of recent randomized clinical trials and systematic reviews.
