日本農村医学会雑誌
Online ISSN : 1349-7421
Print ISSN : 0468-2513
ISSN-L : 0468-2513
農薬中毒の病態生理
第1報有機燐剤中毒と血清コリンエステラーゼ
工藤 尚義
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ジャーナル フリー

1972 年 21 巻 1 号 p. 18-29

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抄録
A study was performed on sickpersons using Alkylphosphates as agricultural chemicals to cultivate apples in the rural sections of Aomori prefecture.
The results obtained can be summarized as follows.
1) In order to diagnose the intoxication of Alkylphosphates, it is very important to measure the serum ChE of farmers having relation with agricultural chemicals.
2) Serum ChE of humans is a unspecial ferment, but it is very useful practicaly to determine serum ChE-rate clinic, aly, instead of special ChE (cell ChE).
3) According to my experiment, the alteration of serum ChE-rate is very faint underΔPh 0.60 of serum ChE-rate, so it is very necessary to determine the pathological limit-line of serum ChE onΔph 0.60 during the investigation of the intoxication of Alkylphosphates.
4) A special finding of serum ChE was found on the observation of serum ChE-rate during the intoxication of Smithion.
5) We have to be careful of mixing of agricultural chemicals also, to avoid the intoxication of Alkylphosphates, in addition to the danger of scattering of them.
6) On account of making confirm the mean of the serum ChE-rate more, it is very necessary to investigate following the ChE-rate continually a long time.
7) After the changing of the Alkylphosphates, having a strong poison, the decrease of sickpersons, suffering of the intoxication of it, is found clearly now.
8) So we have to perform the group-investigation of serum ChE of farmers using agricultural chemicals very soon, because of using a lot of Alkylphosphates since about 20 years, in the rural sections of Aomori prefecture.
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© (社)日本農村医学会
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