1994 年 42 巻 6 号 p. 1146-1151
The severity of carotid arteriosclerosis was evaluated by two-dimensional carotid echography, and the relationship with coronary artery disease and asymptomatic cerebral infarction was studied.
Carotid arteriosclerosis was classified into four types (Category I to IV) by the method of J. T. Salonen et al. The thickness of the carotid intima and media tended to increase with age in healthy individuals, but it almost never exceeded 1 mm even in the elderly.
When the incidende of carotid artery lesions and asymptomatic cerebrel infarction were investigated in 156 subjects, they were present in one out of four Category I subjects, six out of 37 Category II subjects, 49 out of 81 Category III subjects, and 19 out of 27 Category IV. A high incidence of asymptomatic cerebrel infarction was seen in subjects who were Category III or higher.
Coronary artery disease was compared with carotid artery lesions in 118 subjects undergoing coronary angiography. An increase in the severity of carotid arteriosclerosis was associated with an increase in the presence of significant coronary artery stenosis and also with an increase in multivessel coronary disease. There was no difference in the prevalence of carotid arteriosclerosis between subjects with effort angina or myocardial infarction who had only singlevessel disease, but among subjects with multivessel disease those who had effort angina showed more advanced carotid lesions than those with myocardial infarction.
These results indicated a relationship between the severity of carotid arteriosclerosis determined using twodimensional echography and the presence of cerebral infarction and coronary artery disease, suggesting that it is possible to predict the existence of these disease to some extent.