1961 年 9 巻 4 号 p. 308-311
Towards the end of January this year, an eruptive disease, epidemiologically and clinically judged to be Izumi Fever, broke out in the Matsushiro Lower Secondary School. Pupils who fell victims to this disease were as many as 923 persons, corresponding to 62% of the entire school (1491 persons).
While such mass outbreak itself is unusual in the case of Izumi Fever, 55 of such patients had the complication of appendicitis.
The pathogenic agent of this disease is not yet successfully isolated, but many scholars are in one in support of its virus origin. Andthough we do have several reports on the occasional complication of appendicitis in the cases of virus diseases, such mass occurrence is rare.
Results of clinical progress, surgical and histological flndings of the 49 surgically operatedcases among the 55 above-mentioned cases of appendicitis are as follows: 1) considerable hemorrhage inside the appendix lumen and edematous swelling of the local mucosa; 2) existence of necrosis and abscess in some cases; 3) reaction of reticulo lymph cells and slight hemorrhage.