2026 Volume 15 Issue 2 Article ID: 25-073
A 68-year-old man presented to a local hospital with left anterior chest pain. Chest CT revealed an apical lung mass with rib invasion, raising suspicion of primary lung cancer. Transbronchial lung biopsy and four subsequent CT-guided percutaneous biopsies demonstrated fibroblast proliferation with prominent lymphoplasmacytic infiltration, without evidence of malignancy or infection. Based on these findings, a diagnosis of pulmonary inflammatory pseudotumor was made. Treatment with prednisolone led to marked reduction of the mass and complete resolution of chest pain. This case highlights a rare presentation of pulmonary inflammatory pseudotumor with bone invasion, which can closely mimic malignant disease.
