Abstract
With recent advancements in the flexible bronchoscope and cell sampling technique, the preoperative diagnostic rate for peripheral lung cancer is improving. Recently transbronchial lung biopsy-stamp cytology (TBLB-SC) and transbronchial aspiration cytology (TBAC) were employed in our institute and a good preoperative diagnostic rate was obtained, in combination with percutaneous fine needle biopsy (PCNB). We report the preoperative cytodiagnostic rate for peripheral lung cancer in our institute during the past 2 years.
A total of 68 resected peripheral lung cancer were examined. Histologic types of these cases were examined. Histologic types of these cases were 49 adenocarcinomas, 15 squamous cell carcinomas, 2 large cell carcinomas, 1 small cell carcinomas and 1 carcinoid.
Bronchofiberscopy was performed in 67 cases and transbronchial cell sampling was perfomed under bi-plane fluoroscopy. Positive rates for each cell sampling method were as follows. Brushing: 32/47 (68%), TBLB-SC: 48/57 (84%), TBAC: 42/53 (79%). The total transbronchial diagnostic rate was 60/67 (90%). For the negative cases, PCNB was also performed and positive results were obtained in 4 cases. The total preoperative diagnostic rate was 96%.
Transbronchial cell sampling technique combining with TBLB-SC and TBAC was effective for the diagnosis of peripherally originating lung cancer and PCNB was indicated only for transbronchial negative cases. These procedures under transbronchial or percutaneous approaches could not only improve the preoperative diagnostic rate but also accelerate the decision concerning therapy including surgery.
