A Case of Primary Squamous Cell Carcinoma of the Stomach

Abstract

A 69-year-old man was evaluated by his primary physician for a chief complaint of epigastric discomfort in September 2012. Upper GI endoscopy showed a type 2 lesion extending mainly from the gastric cardia to the lesser curvature of the gastric body. A biopsy showed squamous cell carcinoma (SCC). CT showed no evidence of distant metastases or metastases from a cancer of another organ. The patient was diagnosed with primary SCC of the stomach. In October 2012, total gastrectomy (D2 lymph node dissection and p-Roux-en-Y reconstruction) and cholecystectomy were performed. Histopathology showed no evidence of adenocarcinoma or any continuity between the tumor and stratified squamous epithelium of the esophagus. Therefore, a final diagnosis of primary gastric SCC (100×80 mm, pT3 (SS), int, INFb, ly1, v1, pN0, M0, pStage IIA) was made. Postoperative adjuvant chemotherapy with S-1 was given for 1 year. To date, the patient has achieved recurrence-free survival for 3 years and 6 months since surgery. This rare case of primary SCC of the stomach is presented along with a discussion of the relevant literature.