A Case of Follicular Dendritic Cell Sarcoma of the Mesenteric Lymph Node

Abstract

Follicular dendritic cell sarcoma is a rare neoplasm originating from follicular dendritic cells.

A 69-year-old woman presented with right upper abdominal pain. An abdominal computed tomography scan showed a 6 × 6cm well-circumscribed mass which was located anterior to horizontal portion of the duodenum. A duodenal gastrointestinal stromal tumor, a neurogenic tumor of the mesentery, or a neuroendocrine neoplasm arisen in the pancreatic uncinate process was suspected and tumor resection was performed. The tumor was situated in the small bowel mesentery. Microscopically, the tumor consisted of ovoid to spindle-shaped nuclei cells arranged in a diffuse and nest-like pattern. Immunohistochemistry demonstrated that the tumor cells were positive for CD21, CD23, CD35, and D2-40 (only in pleomorphic cells). According to the clinicopathological features, the diagnosis of follicular dendritic cell sarcoma was made. There has been no tumor recurrence as of 8 years of postoperative follow-up.