Two Cases of Successful Anesthetic Management with Landiolol of Elderly Patients with Ischemic Heart Disease

Abstract

We successfully prevented tachycardia and myocardial ischemia with landiolol during anesthesia while undergoing gastrectomy. In both cases, we started continuous infusion of landiolol with relatively low doses at induction of anesthesia. After endotracheal intubation, the patients had hypotension and bradycardia, which was immediately managed with ephedrine and temporary discontinuation of landiolol. There was no significant change in blood pressure and heart rate during extubation. The present cases suggest that landiolol is useful in controlling heart rate during anesthetic management of elderly patients with ischemic heart disease, although careful management is required at induction of anesthesia.