THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA
Online ISSN : 1349-9149
Print ISSN : 0285-4945
ISSN-L : 0285-4945
Invited Lecture
Aging and Postoperative Cognitive Dysfunction
Masataka YOKOYAMA
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JOURNAL FREE ACCESS

2017 Volume 37 Issue 2 Pages 193-200

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Abstract

Aging is the biggest risk factor for postoperative cognitive dysfunction(POCD). With aging, the number of surgeries in elderly people increases, so POCD may become a major social issue. The subject method of evaluating clinical studies of POCD are not yet standardized, and the elucidation of POCD has not advanced. On the other hand, animal studies strongly suggest that neuroinflammation is associated with the onset of POCD. Perioperative care to inhibit neuroinflammation is expected to play a key role in future prophylactic strategies to prevent POCD.

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© 2017 by The Japan Society for Clinical Anesthesia
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