Postoperative Pain and Surgical Site Infection

Abstract

Postoperative pain is induced by tissue injury and influenced by anesthesia and the patient’s background. Although inappropriate analgesia is linked to the incidence of chronic post-surgical pain, analgesics including NSAIDs, opioids, and local anesthetics have immune-suppressive effects, implying that the use of these analgesics may inhibit acute inflammation and the wound healing process, resulting in the occurrence of surgical site infection and delayed wound repair. The correlation between the development of postoperative pain and surgical site infection, and the impact of postoperative analgesia on the outcome, have been indicated in recent years.