Abstract
Objectives : We determination criteria for improving the diagnostic accuracy of suspicious cases in endometrial cytology.
Study Design : Material consisting of 17 cases of NEP, 18 of EGBD, 13 of EH, 6 of AEH, and 16 of G1 was investigated for (1) the frequency of each type of atypical cell clump—dilated or branched pattern, irregular protrusion (proliferative endometrium-like cell type, metaplastic cell type ; papillo-tubular pattern ; (2) frequency of each type of atypical cell clumps—excluded irregular protrusion (metaplastic cell type) ; (3) occurrence of associated features—small clumps of atypical cells, isolated epithelial cells, necrotic background, and squamous metaplastic cells ; (4) the occurrence of more than 20 condensed clusters of stromal cells ; and (5) rediagnosis of 97 suspicious cases.
Results : Certain lesion features were observed : in EH, a predominantly dilated or branched pattern ; in AEH, a predominantly dilated or branched pattern and irregular protrusions (proliferative-like cell type) ; in G1, predominantly irregular protrusions (proliferative-like cell type) ; and a predominantly papillo-tubular pattern. Associated features were significant ; in EGBD, predominantly condensed clusters of stromal cells and irregular protrusions (metaplastic cell type). Of rediagnoses for 97 suspicious cases, 67 (69.1%) agreed with the histological diagnosis.
Conclusions : Our results indicate that a grasp of cell clump features of lesions is useful in improving diagnostic accuracy.
