2009 年 48 巻 4 号 p. 228-229
We analyzed the usefulness of mammaglobin, a breast-cancer-specific immunohistochemical marker, in cytological pleural effusion material. Pleural effusion was immunocytochemically stained for mammaglobin and gross cystic disease fluid protein 15 (GCDFP-15) in 60 subjects, i. e., 20 cases each of breast cancer, lung cancer, and benign. Of breast cancer case fluid, 12 cases (60%) were immunoreactive for mammaglobin and 9 (45%) for GCDFP-15. Combining the two raised breast-cancer identification sensitivity to 70%. The specificity of mammaglobin was 100% and that of GCDFP-15 95%.