We report a case of pulmonary coccidioidomycosis. A 24-year-old American man living in Arizona was found in X-ray imaging and computed tomography (CT) to have an about 20 mm coin-sized right-lung lesion, although specifics were not provided in bronchoscopy. Pulmonary resection yielded a rapid perioperative cytological diagnosis and a frozen tissue specimen. An orange-stained spherule was noted in the cytological specimen.
Fluorescent staining readily detected the spherule, including an endospore. Note that communication with the clinician is required in such rare cases to obtain important clinical information beforehand.