日本臨床細胞学会雑誌
Online ISSN : 1882-7233
Print ISSN : 0387-1193
ISSN-L : 0387-1193
高度異形成, 上皮内癌および微小浸潤癌における細胞診の成績
中山 正博鈴木 公雄副島 研爾下村 守福田 英三山辺 徹
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1971 年 10 巻 2 号 p. 242-246

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The cytological results of 16 severe dysplasias, 58 in situ carcinomas, and 23 minimal invasive carcinomaswere presented in this study. The hystologicaldiagnosis was confirmed by conization specimenor removed uterine cervix.
1) Of 16 severe dysplasias, 4 were positive incytology, 10 were suspicious, and 2 were negative.Of 81 in situ or minimal invasive carcinomas, 53 (65.4%) were positive in cytology, 27 (33.3%) weresuspicious, and one was false negative.
2) Biopsy diagnosis of 80 in situ or minimalinvasive carcinomas were as follows 13 were dysplasia, 62 were in situ carcinoma, and 5 were minimalinvasive carcinoma. One in situ carcinomawas found in a removed uterine cervix, that wasnegative in cytology. 16 severe dysplasias weredecided the same diagnosis by biopsy.
3) Incidence of in situ carcinoma associated withdysplasia was 65.5%, and that of minimal invasivecarcinoma in the same relation was 34.8%.
4) Of 67 in situ or minimal invasive carcinomasdecided the same diagnosis by biopsy, 48 (71.6%) were positive in cytology and 19 (28.4%) weresuspicious. As the results of re-examination ofsmears, 11 suspicious smears were corrected to bepositive. Therefore in this group the positive rateof cytology became high incidence of 88.1%.
5) On the other hand, of 13 in situ or minimalinvasive carcinomas diagnosed as dysplasia by biopsy, 5 (38.5%) were positive in cytology and 8 (61.5%) were suspicious. As 4 suspicious smearswere corrected to be positive after re-examination, the positive rate of cytology in this group became69.2%.
6) 4 in situ carcinomas, suspicious in cytologyeven after re-examination and also its biopsy diagnosesbeing the dysplasia, had relatively small areaof in situ lesion.
We discussed the significance of suspicious smear (class III) and the value of cytology for detectingearly cancer of the uterine cervix.

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